Serial bronchoscopic lung lavage in pulmonary alveolar proteinosis under local anesthesia

Serial bronchoscopic lung lavage in pulmonary alveolar proteinosis under local anesthesia

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Pulmonary alveolar proteinosis (PAP) is a rare disease, characterized by alveolar accumulation of Roper Saddle surfactant composed of proteins and lipids due to defective surfactant clearance by alveolar macrophages.Mainstay of treatment is whole lung lavage, which requires general anesthesia.Herein, we report a case of Mastectomy Bras primary PAP, successfully treated with serial bronchoscopic lung lavages under local anesthesia.